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Polish Biotechnology Sector                                                         Polish Biotechnology Sector


       COMPANY NAME:         Orphninic Scientific SA                                       COMPANY NAME:         Pikralida sp. z o.o.


       WEBSITE :             https://www.orphinic.com/                                     WEBSITE :             https://www.pikralida.eu/en/
       YEAR OF ESTABLISHMENT:  2019                                                        YEAR OF ESTABLISHMENT:  2019
       NUMBER OF EMPLOYEES:  12                                                            NUMBER OF EMPLOYEES:  22
       CERTIFICATIONS:       Our plan is to IPO at Warsaw Stock Exchange by the end of 2023.  CERTIFICATIONS:    not applicable

       PRODUCTS:             Orphinic currently has 10 projects in the pipeline - from a preclinical   PRODUCTS:  Project EpiFix: We are targeting prevention of epilepsy development
                             phase to market approval stages in three healthcare segments:                       following traumatic brain injury or stroke. Initiation of phase I clinical
                             therapeutics, medtech and e-health. Our portfolio represents clinic-                trial is scheduled for H2 2023.  Project ALS: We are running the scientific
                             ready assets, with first projects ready to exit in early 2024, and a                research project to identify the lead structures and a clinical candidate
                             preclinical pipeline for long-term value creation                                   in the next few years.
       FORM OF COOPERATION:  Trade and distribution, Joint Venture, Investment             FORM OF COOPERATION:  Joint Venture, Investment



















                                   Orphinic Scientific S.A. - first Polish biotech portfolio                           Pikralida is conducting scientific projects aimed at the
                                   platform creating innovative solutions for orphan diseases                          discovery and development of breakthrough therapeutic
                                   and other indications with significant unmet medical needs                          solutions offering the response to unmet medical needs of
                                   in the clinical trial phase.  Orphinic core scientific team                         patients. We carry out projects starting from the design of
                                   consist of experts with over 20 years experience in clinical                        an innovative therapeutic solution up to clinical verification
                                   development processes and their commercialization. The                              of the idea in the form of proof-of-concept clinical trials.
                                   company’s competencies in clinical stage development are                            Our portfolio covers the implementation of projects based
                                   further enforced through a collaboration with a large                               on our original concepts, purchased licences, and based on
                                   clinical CRO operating in the CEE region. This facilitates                          the revolutionary discoveries of the academic science
                                   access to diverse patient populations and rapid enrollment                          teams.  We are looking for research collaborations and
                                   to clinical trials supporting our projects and significantly                        partnership with pharmaceutical companies that would
                                   shortens the duration of individual phases.                                         advance clinical development of our lead project.
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